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Chasing "Chasing the Dragon" with MRI: Leukoencephalopathy in Drug Abuse
Br J Radiol 78:997-1004, Bartlett,E. &Mikulis,D.J., 2005
See this aricle in Pubmed

Article Abstract
In conclusion: (1) All three cases have MR findings suggestive of spongiform leukoencephalopathy. MRS may help differentiate toxicity due to inhaled heroin from other non-heroin related toxicities. (2) Discordance between perfusion and spectroscopy in one chasing patient adds evidence that the disease is due to impaired energy metabolism at the cellular level. (3) MR findings of spongiform leukoencephalopathy secondary to chasing heroin can progress despite apparent abstinence of the drug and during clinical improvement, suggesting that MR changes may represent an evolving injury.
 
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addiction,heroin
brainstem
brainstem,lesion of
cerebellar lesion
cerebellum
chasing the dragon
differential diagnosis
disability,neurological
leukoencephalopathy
leukoencephalopathy,toxic
mortality
MRI,abnormal
MRI,diffusion weighted
MRS
prognosis
white matter disease

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